Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

X-ray Crystallography02:18

X-ray Crystallography

23.8K
The size of the unit cell and the arrangement of atoms in a crystal may be determined from measurements of the diffraction of X-rays by the crystal, termed X-ray crystallography.
Diffraction
Diffraction is the change in the direction of travel experienced by an electromagnetic wave when it encounters a physical barrier whose dimensions are comparable to those of the wavelength of the light. X-rays are electromagnetic radiation with wavelengths about as long as the distance between neighboring...
23.8K
X-ray Diffraction of Biological Samples01:10

X-ray Diffraction of Biological Samples

3.8K
X-ray diffraction or XRD is an analytical tool that utilizes X-rays to study ordered structures such as crystalline organic and inorganic samples, polycrystalline materials, proteins, carbohydrates, and drugs.
According to Bragg's law, when X-rays strike the sample positioned on a stage, the rays are  scattered by the electron clouds around the sample atoms. The  X-ray diffraction or scattering is caused by constructive interference of the X-ray waves that reflect off the internal...
3.8K

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Report of high data rate macromolecular crystallography (HDRMX) meeting, 23 July 2025.

Structural dynamics (Melville, N.Y.)·2026
Same author

P<sup>3</sup>, linearizing unit-cell parameters.

Acta crystallographica. Section A, Foundations and advances·2026
Same author

Approximate lattice matching in three dimensions.

Acta crystallographica. Section A, Foundations and advances·2026
Same author

Regional and National Shared Research Resources: Challenges and Opportunities§.

Journal of biomolecular techniques : JBT·2026
Same author

Structural biology at the National Synchrotron Light Source II.

Journal of synchrotron radiation·2025
Same author

Massive compression for high data rate macromolecular crystallography (HDRMX): impact on diffraction data and subsequent structural analysis.

Journal of synchrotron radiation·2025

相关实验视频

Updated: Jun 12, 2025

An All-in-one Sample Holder for Macromolecular X-ray Crystallography with Minimal Background Scattering
07:55

An All-in-one Sample Holder for Macromolecular X-ray Crystallography with Minimal Background Scattering

Published on: July 6, 2019

13.2K

大规模压缩用于高数据速率宏分子结晶学 (HDRMX):对衍射数据和随后的结构分析的影响.

Herbert J Bernstein, Alexei S Soares, Kimberly Horvat

    bioRxiv : the preprint server for biology
    |September 24, 2024
    PubMed
    概括

    新的X射线探测器产生了大量的数据. 像JPEG-2000和Hcompress这样的损耗压缩算法可以最大限度地减少结构生物学实验中的数据损失,并保留结构解决方案的基本信息.

    科学领域:

    • 晶体学 晶体学是指结晶学.
    • 结构生物学 结构生物学
    • 数据科学数据科学数据科学

    背景情况:

    • 高计数率的X射线探测器正在出现,使得数据采集速度更快.
    • 增加的数据吞吐量需要高效的数据压缩,用于专门的宏分子X射线 (MX) 实验.

    研究的目的:

    • 评估高容量X射线探测器数据的损耗压缩算法.
    • 确定最小化信息损失的方法,同时保持MX实验的结构完整性.

    主要方法:

    • 研究了图像总和和像素组合技术.
    • 评估了JPEG-2000 (基于波段) 和Hcompress (基于Haar波段) 的损耗压缩.
    • 探索了总和,分类和压缩算法的组合.

    主要成果:

    • 无论是JPEG-2000还是Hcompress都提供有效的损耗压缩.
    • 组合方法 (总和,分类,压缩) 成功保留了关键的结构信息.
    • 压缩级别可以调整以平衡文件大小和数据完整性.

    结论:

    • 在MX实验中,对于高通量X射线探测器数据来说,损耗压缩是可行的.

    更多相关视频

    Workflow and Tools for Crystallographic Fragment Screening at the Helmholtz-Zentrum Berlin
    06:29

    Workflow and Tools for Crystallographic Fragment Screening at the Helmholtz-Zentrum Berlin

    Published on: March 3, 2021

    5.4K
    Biochemical and Structural Characterization of the Carbohydrate Transport Substrate-binding-protein SP0092
    08:53

    Biochemical and Structural Characterization of the Carbohydrate Transport Substrate-binding-protein SP0092

    Published on: October 2, 2017

    29.9K

    相关实验视频

    Last Updated: Jun 12, 2025

    An All-in-one Sample Holder for Macromolecular X-ray Crystallography with Minimal Background Scattering
    07:55

    An All-in-one Sample Holder for Macromolecular X-ray Crystallography with Minimal Background Scattering

    Published on: July 6, 2019

    13.2K
    Workflow and Tools for Crystallographic Fragment Screening at the Helmholtz-Zentrum Berlin
    06:29

    Workflow and Tools for Crystallographic Fragment Screening at the Helmholtz-Zentrum Berlin

    Published on: March 3, 2021

    5.4K
    Biochemical and Structural Characterization of the Carbohydrate Transport Substrate-binding-protein SP0092
    08:53

    Biochemical and Structural Characterization of the Carbohydrate Transport Substrate-binding-protein SP0092

    Published on: October 2, 2017

    29.9K
  • 优化的压缩策略保留了结构解决方案的必不可少的布拉格反射数据.
  • 在现代晶体学中,先进的压缩技术对于管理大型数据集至关重要.