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Updated: Jun 12, 2025

Measuring Enzymatic Activity of Neurodevelopmental Disorder-Associated Deubiquitylating Enzymes via an In Vitro Ubiquitin Chain Cleavage Assay
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Measuring Enzymatic Activity of Neurodevelopmental Disorder-Associated Deubiquitylating Enzymes via an In Vitro Ubiquitin Chain Cleavage Assay

Published on: September 27, 2024

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在VCP,一个重要的unfoldase和deubiquitinases之间有不同的合模式

Lauren E Vostal, Noa E Dahan, Wenzhu Zhang

    bioRxiv : the preprint server for biology
    |September 24, 2024
    PubMed
    概括

    这项研究揭示了蛋白质循环酶VCP如何与诸如VCPIP1之类的二维基因酶 (DUB) 协调在不同的部位. 这种协调对于管理无处不在的蛋白质,影响衰老和疾病至关重要.

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