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Updated: Jun 12, 2025

Implementing Patch Clamp and Live Fluorescence Microscopy to Monitor Functional Properties of Freshly Isolated PKD Epithelium
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Published on: September 1, 2015

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在PKD2孔螺旋中的ADPKD变异会导致门的结构崩和不同的道功能障碍形式

Orhi Estarte Palomero, Paul G DeCaen

    bioRxiv : the preprint server for biology
    |September 24, 2024
    PubMed
    概括

    自体主导多囊性病 (ADPKD) 是由PKD2基因变异引起的. 这项研究揭示了ADPKD变体的独特PKD2通道失调机制,指导了未来的治疗开发.

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