皮表皮生长因子受体信号控制宿主对侵入性阿斯伯吉洛症的炎症反应

Hong Liu1, Jianfeng Lin1, Quynh T Phan1

  • 1Division of Infectious Diseases, Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA, United States of America.

概括

皮表皮生长因子受体 (EGFR) 信号传递对抗Aspergillus fumigatus肺部感染的先天免疫反应至关重要. 阻断EGFR会影响真菌清除,并增加免疫抑制小鼠的死亡率.

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