遥远感官多神经病变的严重程度随着艾滋病毒/艾滋病阶段的增加而增加
Andi Weri Sompa1, Yudy Goysal2, Muhammad Akbar2
1Neurology Department, Faculty of Medicine and Health Sciences, Universitas Muhammadiyah Makassar, Makassar, Indonesia.
The Pan African medical journal
|September 24, 2024
概括
距离感官多神经病 (DSP) 在艾滋病毒/艾滋病患者中很常见. 晚期的艾滋病毒/艾滋病阶段与增加的DSP严重程度有显著的相关性,表明需要监测.
科学领域:
- 神经学 神经学
- 传染性疾病 传染性疾病
- 公共卫生 公共卫生
背景情况:
- 距离感官多神经病变 (DSP) 是艾滋病毒/艾滋病患者常见的神经并发症.
- DSP的发病过程复杂,涉及与先进的艾滋病毒疾病和抗逆转录病毒疗法相关的外周神经损伤,线粒体毒性成为潜在的原因.
- 了解与DSP严重程度相关的因素对于管理这种常见疾病至关重要.
研究的目的:
- 研究与患有艾滋病毒/艾滋病的患者中偏远感官多神经病变 (DSP) 严重程度相关的因素.
- 确定艾滋病毒阳性队列中临床参数和DSP严重程度之间的潜在相关性.
主要方法:
- 一项涉及印度尼西亚马卡萨尔50名艾滋病毒/艾滋病门诊患者的横截面研究.
- DSP的诊断和严重程度评估使用了非侵入性主观外围神经病变屏幕 (SPNS).
- 统计分析包括皮尔森的千平方和斯皮尔曼的相关性测试,以评估变量和DSP严重程度之间的关联.
主要成果:
- 86%的参与者 (50人中有43人) 被诊断为DSP,主要是中度严重的 (48%).
- 在艾滋病毒/艾滋病的阶段和DSP严重程度之间发现了显著的相关性 (p=0.032).
- 在DSP严重程度和CD4计数,抗逆转录病毒使用,体重指数 (BMI) 或血红蛋白水平之间没有发现显著的相关性.
结论:
- 艾滋病毒/艾滋病阶段是与DSP严重性的重要相关因素.
- 艾滋病毒/艾滋病的进展与远端感官多神经病变的严重程度增加相关.
- 这些发现凸显了在DSP的临床评估中考虑艾滋病毒/艾滋病分期的重要性.
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