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Updated: Jul 11, 2026

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在人类中,持续的神经生长因子诱导的C-nociceptor对电动鼻状刺激的敏感化

Hans Jürgen Solinski1, Martin Schmelz1, Roman Rukwied1

  • 1Department of Experimental Pain Research, Mannheim Center for Translational Neuroscience, Medical Faculty Mannheim, University of Heidelberg, Heidelberg, Germany.

Pain reports
|September 24, 2024
PubMed
概括

再组合的人类神经生长因子 (rhNGF) 导致C-nociceptors的长期敏感,导致慢性疼痛. 这项研究揭示了rhNGF诱导的超刺激性在机械敏感和机械不敏感的疼痛通路中.

关键词:
热传导传导是一种热传导.过敏症是一种过敏症.炎症 炎症是一种炎症.多种模式的感知器.

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Local Anesthetics: Differential Sensitivity of Nerve Fibers01:24

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Local anesthetics (LAs) block the sodium channels of nerve trunks, sensory nerve endings, and neuromuscular junctions. Although LAs can block all kinds of nerves, the sensitivity of nerve fibers differs according to nerve types and structures. LAs are known to block myelinated fibers faster than unmyelinated ones. Also, they block pain or sensory neurons at low concentrations without affecting the motor neurons involved in muscle contractions. This helps relieve labor pain without affecting the...