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比较祖先标准化方法的跨祖先结肠直肠癌多基因风险评分

Elisabeth A Rosenthal1, Li Hsu2, Minta Thomas2

  • 1Division Medical Genetics, School of Medicine, University of Washington, Seattle, Washington, USA.

Genetic epidemiology
|September 24, 2024
PubMed
概括

在祖先之间对结直肠癌 (CRC) 的多基因风险评分 (PRS) 的标准化至关重要. 使用祖先多样化的训练集和混合物作为共变量,可以创建可靠的PRSz-score来识别高风险个体.

关键词:
添加剂 混合物 添加剂我们所有人,我们所有人.结肠直肠癌是什么意思多基因风险评分多基因风险评分.跨血统的人.

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