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Updated: Jun 12, 2025

Real-time Observation of the DNA Strand Exchange Reaction Mediated by Rad51
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Real-time Observation of the DNA Strand Exchange Reaction Mediated by Rad51

Published on: February 13, 2019

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切换式酸化WRN将终端切割与RAD51代谢在崩的复制分叉中整合在一起

Valentina Palermo1, Eva Malacaria1, Maurizio Semproni1

  • 1Department of Environment and Health, Mechanisms, Biomarkers and Models Section, Genome Stability Group, Istituto Superiore di Sanità, Viale Regina Elena 299, 00161 Rome, Italy.

Nucleic acids research
|September 24, 2024
PubMed
概括

通过CDK1,ATM和ATR激酶对WRN螺旋酶的有序酸化调节了DNA双链断裂的修复. 这种调节对于终端切除和同源重组 (HR) 途径的选择至关重要.

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