蛇形动脉瘤的综合评估:系统审查和元分析,并对治疗方法进行次分析
Celal Cinar1, Alperen Elek2, Irshad Allahverdiyev3
1Department of Interventional Radiology, Faculty of Medicine, Ege University, 35100, Izmir, Turkey.
Clinical neuroradiology
|September 24, 2024
概括
这次审查评估了蛇形动脉瘤的管理策略. 重建性和解构性内血管治疗都提供了良好的神经学结果,并可接受的并发症率.
科学领域:
- 神经学 神经学
- 干预性神经放射学 干预性神经放射学
- 血管外科 血管外科
背景情况:
- 蛇形动脉瘤是复杂的血管形,需要专门的管理.
- 最佳的治疗策略仍然是正在进行的研究和临床辩论的主题.
研究的目的:
- 系统地审查和综合有关蛇形动脉瘤管理的证据.
- 增强对与不同治疗方式相关的临床和血管学结果的理解.
主要方法:
- 在主要数据库 (Medline,Scopus,Cochrane) 进行了系统的文献搜索,直到2024年7月.
- 包括的研究包括案例系列,队列研究和随机对照试验,重点关注内蛇形动脉瘤.
- 数据提取和质量评估是独立进行的,使用随机效应模型进行统计分析.
主要成果:
- 分析了10项涉及70名患者和71名蛇形动脉瘤的研究;大多数是巨型动脉瘤.
- 总体而言,与手术相关的并发症,发病率和死亡率分别为33%,13%和13%,神经学结果良好率为76%.
- 与解构方法 (70%) 相比,重建性内血管方法的良好神经结果率略高 (77%),并出现类似的并发症率.
结论:
- 内血管治疗,包括重建和解构方法,对于蛇形动脉瘤是有效的.
- 这些治疗方法实现了较高的有利神经结果率,并呈现了可接受的并发症概况.
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