在PET图像中[18F]甲醇PET图像的视觉读数中,interrater协议和变异性
Akinori Takenaka1,2, Takashi Nihashi2, Keita Sakurai2
1Department of Radiology, Fujita Health University School of Medicine, Toyoake, Japan.
Annals of nuclear medicine
|September 24, 2024
概括
粉样蛋白PET扫描的视觉评分显示专家之间存在很高的共识,但中间情况需要仔细解释. 百叶状物尺度值与 [18F] 弗拉特梅塔莫尔粉样蛋白成像的评级者共识相关.
科学领域:
- 神经学 神经学
- 核医学就是核医学.
- 放射学 放射学是一门学科.
背景情况:
- 粉样蛋白正子发射断层扫描 (PET) 成像对于诊断阿尔茨海默病至关重要.
- 粉样蛋白PET扫描的视觉评估是解释的一个常见方法.
- 视觉读取的标准化对于可靠的诊断至关重要.
研究的目的:
- 为了验证视觉评级对 [18F] 甲醇粉样蛋白PET图像的一致性.
- 为了评估评价者协议与百分点 (CL) 尺度之间的相关性.
主要方法:
- 192名参与者 (认知正常,MCI,AD,非AD痴呆症) 接受了粉样蛋白PET成像.
- 三位专家进行了视觉评级,以信任级别.
- 百叶状体 (CL) 值是使用CapAIBL管道计算的.
主要成果:
- 对于视觉评分,观察到高interrater可靠性 (kappa=0.83).
- 在92%的阳性扫描和82%的负性扫描中,完全达成一致.
- 评级者不同意的图像显示了中间的CL值,较低的信心与较高的不同意相关.
结论:
- 对[18F] 弗拉梅他胺胺PET扫描的视觉解释表明,它们之间的一致性很高.
- 在患者中介性粉样蛋白积累的视觉读取建议谨慎.
- 百分尺度提供了与视觉评估和评价者信心相关的定量衡量标准.
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