自动化系统从多种类型的日本临床文本捕获患者症状:回顾性研究
Tomohiro Nishiyama1, Ayane Yamaguchi2, Peitao Han1
1Department of Information Science, Nara Institute of Science and Technology, Ikoma, Japan.
JMIR medical informatics
|September 24, 2024
概括
这项研究开发了一种自然语言处理 (NLP) 系统,用于从多种电子健康记录文件类型中检测药物不良事件 (ADEs). 与单一文档分析相比,利用各种文件提高了ADE检测的准确性.
科学领域:
- 医疗信息学 医疗信息学
- 自然语言处理自然语言处理.
- 临床数据分析 临床数据分析
背景情况:
- 电子健康记录 (EHR) 包含有价值的患者数据,包括药物不良事件 (ADE) 信号.
- 分析不同类型的EHR文件 (如医生笔记,护理记录) 对于全面评估患者状态至关重要.
- 当前的方法往往孤立分析文档,可能缺少关键信息.
研究的目的:
- 开发和评估一种自然语言处理 (NLP) 系统,用于检测多种EHR文档类型中的ADEs.
- 评估系统在识别乳腺癌患者的外围神经病变 (PN) 作为ADE的性能.
- 为了比较分析多种类型的EHR文档与单种类型的ADE检测文档的有效性.
主要方法:
- 开发了一种NLP系统,处理6种类型的日本EHR文件:医生笔记,出院摘要,放射学报告,放射性同位素报告,护理记录和药剂师笔记.
- 该系统包括命名实体识别,症状正常化和从多个文档和患者的数据汇总.
- 使用2289名乳腺癌患者的数据评估系统性能,重点关注帕克利塔塞尔或多塞塔塞尔诱导的PN,通过相关系数和回归分析评估性能.
主要成果:
- 在60.7%的病例中,NLP系统检测到帕克利塔塞尔诱导的PN,与之前的手动提取 (74.0%) 相比,略低估计.
- 在系统结果和手动提取之间观察到高的皮尔森相关系数 (0.87).
- 虽然药剂师笔记显示了最高的个体检测率,但所有文档类型的汇总数据与单一类型的分析相比,显著改善了整体性能.
结论:
- 开发的NLP系统有效地利用多种类型的EHR文档来提高ADE检测的准确性.
- 这种方法具有显著的优势,因为它可以快速估计治疗持续时间 (例如,对于PN),而不需要对新模型进行微调.
- 这些发现强调了整合各种临床数据源的价值,以实现更强大的ADE监测和患者护理.
关键词:
欧洲人权理事会 欧洲人权理事会电子人权 (EHRs) 是一种电子人权.ML ML 在 ML在NLP中,我们使用了NLP.负面的负面影响药物不良反应 药物不良反应不良事件是不良事件.癌症 癌症 癌症 癌症 癌症发现 发现 发现 发现 发现检测到检测到的检测.检测 检测 检测 检测 检测毒品 毒品 毒品 是一种药物.药物 药物 药物 药物 药物 药物机器学习是机器学习.药物治疗 药物治疗药物 药物 药物 药物命名实体的认可 命名实体的认可自然语言处理自然语言处理.神经病变是一种神经病变.在这里,我们可以看到注意事项,注意事项.笔记 笔记 笔记 笔记 笔记瘤学 在瘤学方面.周边神经病变是一种神经病变.药物制造业的制药公司制药公司的药品.药品制品制品制品制品制品制品制品制品药品制药公司 药品制药公司药理学 药理学 药理学 药理学 药理学药物治疗药物治疗记录记录记录记录记录记录记录记录 记录 记录 记录 记录报告报告报告报告报告.报告报告报告报告报告报告.这是一个症状,一个症状.症状 症状 症状 症状 症状文本 文本 文本文本是文本,文本是文本.文本性 文本性 文本性相关概念视频
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