集体认知行为心理治疗对炎症性肠病患者疾病严重程度和心理社会功能的影响:一项随机对照研究
Maria Kalogeropoulou1, Katerina Karaivazoglou1, Georgia Konstantopoulou1
1Department of Psychiatry, University Hospital of Patras, Patras, Greece.
Journal of Crohn's & colitis
|September 24, 2024
概括
认知行为疗法显著改善了炎症性肠病 (IBD) 患者的心理痛苦,并减少了炎症. 这种整体方法提高了IBD患者的生活质量和临床结果.
科学领域:
- 胃肠病学 胃肠病学
- 精神病学是一个精神病学.
- 临床医学 临床医学
背景情况:
- 炎症性肠病 (IBD) 经常与心理困扰有关,包括焦虑和抑郁,以及生活质量 (QoL) 的下降.
- 关于心理治疗对IBD患者心理健康和临床状况的影响的研究有限.
研究的目的:
- 评估一个简短的群体认知行为疗法 (CBT) 干预的疗效.
- 评估CBT对心理痛苦,生活质量,性功能以及IBD患者炎症和疾病活动的客观措施的影响.
主要方法:
- 一项前性随机对照试验,涉及80名IBD患者.
- 参与者被分配到一组CBT或通常的治疗 (控制组).
- 评估包括心理痛苦的心理测量仪器,QoL,性功能和实验室标记 (CRP,细胞因子,calprotectin) 以及基线和6个月的疾病活动指数.
主要成果:
- 心理治疗患者的焦虑和抑郁症显著减少.
- 在身体功能,一般健康,活力,社会功能和心理健康方面观察到改善.
- 与对照组相比,CBT组的C-反应性蛋白 (CRP) 水平和克罗恩病活动指数 (CDAI) 显著下降.
结论:
- 群体认知行为疗法是整体IBD患者护理的宝贵补充.
- CBT可以显著提高心理社会功能,并积极影响IBD的临床过程.
- 该干预措施显示出抑制炎症和减少IBD患者的疾病活性的能力.
相关概念视频
Inflammatory Bowel Disease IV: Pharmacological Management
118
Upon diagnosis, managing Inflammatory Bowel Disease (IBD) involves addressing several crucial aspects. The primary goals include resting the bowel, correcting malnutrition, and providing symptomatic relief. Resting the bowel may consist of medications to reduce inflammation and promote healing. Correcting malnutrition is essential, often requiring dietary adjustments and nutritional supplements. Symptomatic relief aims to ease pain, diarrhea, and other discomforts in IBD.
Pharmacologic...
Pharmacologic...
118
Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy
323
Various diagnostic tests are employed in the diagnostic process for Inflammatory Bowel Disease (IBD), particularly to differentiate between Crohn's disease and ulcerative colitis.
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the...
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the...
323
Inflammatory Bowel Disease II: Crohn's Disease
200
Introduction
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by...
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by...
200
Chronic Bowel Disorders: Introduction
408
Chronic bowel diseases are a group of long-term conditions affecting the digestive tract, characterized by inflammation and damage to the gut lining. These conditions primarily include irritable bowel syndrome and inflammatory bowel disease.
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
408
Drugs for Treatment of Crohn's Disease in IBD Using Glucocorticoids
98
Glucocorticoids, a class of anti-inflammatory drugs, are pivotal in treating moderate to severe Crohn's disease by inducing remission. They exhibit their anti-inflammatory action by inhibiting the production of inflammatory cytokines such as tumor necrosis factor (TNF)-α, interleukin (IL)-1, and chemokines like IL-8. In addition, they reduce the expression of inflammatory cell adhesion molecules and inhibit gene transcription of nitric oxide synthase, phospholipase A2, cyclooxygenase-2...
98
Drugs for Treatment of Crohn's Disease in IBD Using Immunomodulatory Agents
145
Crohn's disease is an inflammatory bowel disorder marked by chronic inflammation of the GI tract. Various treatment strategies for Crohn's disease are employed, such as immunomodulatory agents, glucocorticoids, and biologics or anti-TNF therapy. Azathioprine (Imuran), a commonly used immunomodulatory drug for Crohn's disease, is converted in the body to mercaptopurine, which inhibits purine biosynthesis and cell proliferation. Both are utilized in severe cases of Inflammatory Bowel...
145


