相关实验视频

Updated: Jun 12, 2025

Investigation of the Transcriptional Role of a RUNX1 Intronic Silencer by CRISPR/Cas9 Ribonucleoprotein in Acute Myeloid Leukemia Cells
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Investigation of the Transcriptional Role of a RUNX1 Intronic Silencer by CRISPR/Cas9 Ribonucleoprotein in Acute Myeloid Leukemia Cells

Published on: September 1, 2019

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协同转录拼接的破坏表明RBM39是急性淋巴细胞白血病的治疗点

Qi Jin1, Ethan Harris2, Jacquelyn A Myers3

  • 1Department of Hematology, St. Jude Children's Research Hospital, Memphis, TN.

Blood
|September 24, 2024
PubMed
概括

用特定的抑制剂向RBM39基因显示出治疗复发性/耐药B细胞急性淋巴细胞白血病 (B-ALL) 的前景. 这种方法降解RBM39蛋白质,抑制癌症生长,并提供新的治疗策略.

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