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Updated: Jun 12, 2025

Microwave-Assisted Preparation of 1-Aryl-1H-pyrazole-5-amines
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具有硫胺末端部分的新型乙烯醇衍生物的抗癌和抗炎作用

Mohammed S Abdel-Maksoud1, Shaimaa A Nasser1, Rasha M Hassan1

  • 1Medicinal &Pharmaceutical Chemistry Department, Pharmaceutical and Drug Industries Research Institute, National Research Centre (NRC), P.O. 12622, Dokki, Giza, Egypt.

Bioorganic chemistry
|September 24, 2024
PubMed
概括

合成了含有硫胺基的新型火醇化合物,并对其酶抑制和抗炎活性进行了评估. 化合物23b,23c和23d显示出显著的JNK和BRAF抑制,而化合物23b显示出广泛的细胞系活性.

关键词:
抗炎药物 抗炎药物 抗炎药物抗扩散药物 抗扩散药物简基因酶抑制剂 简基因酶抑制剂皮拉 (Pyrazole) 是一种可怕的药物.硫胺是什么?硫胺是什么?

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