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Updated: Jun 12, 2025

De novo Identification of Actively Translated Open Reading Frames with Ribosome Profiling Data
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替代翻译启动产生具有独特本地化和功能的突触组织者蛋白质形式

Paul Jongseo Lee1, Yu Sun2, Alexa R Soares3

  • 1Department of Neuroscience, Yale University School of Medicine, New Haven, CT 06510, USA; Interdepartmental Neuroscience Program, Yale University, New Haven, CT 06520, USA.

Molecular cell
|September 24, 2024
PubMed
概括

在信使RNA (mRNA) 中的替代翻译启动站点创建不同的蛋白质版本. 这项研究揭示了这一过程如何影响小鼠的神经元功能和学习行为.

关键词:
在AMPA受体上,AMPA受体是结构 RNA 结构 RNA 结构神经元中的中毒素.形成蛋白质的蛋白质形式.核糖体的核糖体是指核糖体中的核糖体.分泌蛋白质是分泌的蛋白质.信号序列的信号序列.突触组织者的突触组织者.开始翻译 开始翻译跨膜域域是一个跨膜域.

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