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Updated: Jun 12, 2025

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痕信号调节了代谢功能障碍相关的脂肪性肝病中巨细胞介导的炎症

Wei Guo1, Ziyi Li2, Gerasimos Anagnostopoulos3

  • 1Shanghai Institute of Immunology, Department of Immunology and Microbiology, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China; Department of General Surgery, Pancreatic Disease Center, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China; Research Institute of Pancreatic Diseases, Shanghai Key Laboratory of Translational Research for Pancreatic Neoplasms, Shanghai Jiao Tong University School of Medicine, Shanghai, China.

Immunity
|September 24, 2024
PubMed
概括

诺奇-RBPJ途径控制了在代谢功能障碍相关的脂肪性肝病 (MASLD/MASH) 中肝细胞巨的发育. 其缺乏促进保护性单细胞,为肝病提供新的治疗点.

关键词:
库弗弗细胞是库弗弗细胞.Ly6C(hi) 单细胞的一体细胞.Ly6C ((lo) 单细胞的一种.马什 (MASH) 是一个非常重要的产品.没有口,没有口.在 RBPJJ 里面.这是一种炎症炎症炎症炎症.肝脏 肝脏 肝脏 肝脏 肝脏 肝脏巨细胞是一个巨细胞.一个单细胞单细胞.

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