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In vitro Digestion of Emulsions in a Single Droplet via Multi Subphase Exchange of Simulated Gastrointestinal Fluids
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体结构的表征及其可溶性潜力BCSII类药物在空腹状态模拟肠液中的BCSII类药物

Zoe McKinnon1, Ibrahim Khadra1, Gavin W Halbert1

  • 1Strathclyde Institute of Pharmacy and Biomedical Sciences, University of Strathclyde, 161 Cathedral Street, Glasgow, G4 0RE, United Kingdom.

International journal of pharmaceutics
|September 24, 2024
PubMed
概括

药物在模拟肠液 (SIF) 中的溶解性随着两性度的增加而增加,而酸性药物是最容易溶解的. 体结构的大小因SIF成分而异,影响药物溶解度.

关键词:
动态光散射是一种动态光散射.禁食状态 禁食状态肠道液体 肠道液体纳米粒子跟踪分析分析颗粒大小 颗粒大小可溶性 可溶性 溶性

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