将纤维素纳米晶体的胃空化与藻酸盐和pectin进行比较,使用一个动态的体外胃模型
Jiannan Feng1, Zijin Qin1, Azin Farmanfarmaee1
1Department of Food Science and Technology, University of Georgia, United States of America.
International journal of biological macromolecules
|September 24, 2024
概括
纤维素纳米晶 (CNC) 通过形成凝,显著延缓胃排空,与酸盐和pectin不同. 这种食纤维通过增强腹感,显示出对体重管理的前景.
科学领域:
- 食品科学与技术 食品科学与技术
- 生物材料科学 生物材料科学
- 营养科学 营养科学
背景情况:
- 纤维素纳米晶体 (CNC) 具有对pH值和离子强度敏感的凝特性.
- 这些特性表明,在调节肥胖和糖尿病管理的胃空化和腹感方面,有潜在的应用.
- 众所周知,食纤维如阿尔金酸盐和果会影响胃肠功能.
研究的目的:
- 为了研究纤维素纳米晶体 (CNC) 对胃空化的作用,与藻酸盐和pectin相比.
- 探索双价离子 (Ca2+和Mg2+) 在CNC诱导的胃空化的变化中的作用.
- 评估CNC作为通过增强腹感来控制体重的食纤维的潜力.
主要方法:
- 利用动态胃消化模型来模拟人类的胃状况.
- 在存在Ca2+和Mg2+的情况下,评估了CNC (4%和8%重/重),藻酸盐 (2%重/重) 和pectin (2%重/重) 的胃空化率.
- 测量了每次治疗的胃空化的半衰期 (t1/2).
主要成果:
- CNC,特别是8%的Ca2+,形成了高粘度的凝,显著延迟了胃排空 (t1/2 = 215.4 ± 23.7分钟).
- 酸形成了含有Ca2+的凝,但由于持水能力差,没有显著延迟排空.
- 素对胃排空的影响很小 (t1/2 = 15.1 ± 1.4 分钟).
结论:
- 纤维素纳米晶比酸盐和pectin更有效地延迟胃排空并促进胃的保留.
- 通过双价离子增强的CNC的凝机制,有助于其在增强腹感方面的有效性.
- CNC介绍了一种有前途的食纤维,用于帮助体重管理,并为动态胃消化模型提供了一种新的应用.
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