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Updated: Jun 12, 2025

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自然资源中的多糖:制备,净化,结构阐明,结构-活性关系和调节肠道菌群,系统审查

Di Han¹, Le Yang², Qichao Liang¹

¹State key laboratory of Integration and Innovation of Classic Formula and Modern Chinese Medicine, National Chinmedomics Research Center, National TCM Key Laboratory of Serum Pharmacochemistry, Metabolomics Laboratory, Department of Pharmaceutical Analysis, Heilongjiang University of Chinese Medicine, Heping Road 24, Harbin 150040, China.

International journal of biological macromolecules

|September 24, 2024

概括

天然资源多糖化物 (NRPs) 是多功能化合物,在医学,食品和农业方面具有重大潜力. 本综述综合了NRP制备,结构,生物活性和肠道健康应用方面的最新进展.

科学领域:

生物化学和自然产品化学化学
食品科学与技术食品科学与技术
农业科学农业科学
微生物学和肠道健康

背景情况:

自然资源多糖化物 (NRPs) 是各种生物体中发现的丰富的生物聚合物,表现出不同的生物活动和结构性质.
目前对NRP的研究是分散的,重点是特定的多糖,而不是提供一个整体的领域的概述.
需要一个全面的摘要来巩固最近的进展,并指导未来的NRP的研究和开发.

研究的目的:

为过去五年中自然资源多糖化物 (NRPs) 研究的最新进展提供全面的回顾.
分析制备,净化,结构阐明,结构-活性关系,以及NRPs在调节肠道菌群中的作用.
突出NRPs在促进肠道微生态平衡方面的潜力,以及其作为益生菌启动剂的应用.

主要方法:

在过去五年内在电子数据库 (PubMed,Wiley,ScienceDirect,Web of Science) 中发表的NRP研究的系统文献综述.
分析各种提取技术及其对NRP特性的影响.
研究NRP结构与生物活性之间的相关性,包括化学修饰的影响.

主要成果:

提取技术显著影响NRP特性和生物活性.
对NRP的化学修饰可以增强结构多样性,从而导致新的或改进的生物功能.
在促进肠道微生态平衡方面,NRPs具有显著的潜力,作为有效的益生菌启动剂.

结论:

本综述整合了最近关于NRP的发现,涵盖了它们的制备,结构分析,生物活性和肠道健康应用.
在医学,食品和农业领域,NRPs具有相当大的发展潜力,特别是调节肠道微生物群.
这些发现为未来的NRP的研究和工业应用提供了理论基础.

关键词:

肠道菌群是什么意思肠道菌群自然资源中的多糖类.结构阐明结构阐明结构修改是指结构的修改.结构与活动之间的关系.

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