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Updated: Jun 12, 2025

Determining the Likelihood of Variant Pathogenicity Using Amino Acid-level Signal-to-Noise Analysis of Genetic Variation
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与阿拉伯人口中的临床算法相比,国际验证的基因引导华法林剂量算法的准确性

Amr M Fahmi1, Ahmed El Bardissy1, Mohamed Omar Saad1

  • 1Pharmacy Department, Hamad Medical Corporation, Doha, Qatar.

Current problems in cardiology
|September 24, 2024
PubMed
概括

在阿拉伯患者中,CYP2C9和VKORC1的遗传变异显著影响华法林剂量. 基因华法林剂量 (GWD) 算法提供了比单独临床剂量更准确的华法林剂量估计.

关键词:
在CYP2C9中.在CYP4F2中.临床华法林剂量 临床华法林剂量基因指导的华法林剂量这就是VKORC1的原因.华法林/使用和剂量

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