自然产品和衍生品作为日本脑炎病毒抗病毒药物
Yunqi Mi1, Yan Guo2, Xuliang Luo3
1The Xi'an Key Laboratory of Pathogenic Microorganism and Tumor Immunity, School of Basic Medicine, Xi'an Medical University, Xi'an 710021, China.
Pathogens and disease
|September 24, 2024
概括
日本脑炎病毒 (JEV) 在全球引起严重疾病和死亡. 本综述探讨了天然产品作为开发急需的抗JEV药物的有希望的来源,以补充目前的疫苗.
科学领域:
- 病毒学 病毒学
- 传染性疾病 传染性疾病
- 药理学 药理学是指药理学的学科.
背景情况:
- 日本脑炎病毒 (JEV) 导致日本脑炎 (JE),这是一个重要的全球健康问题,死亡率高和神经系统的后果.
- 每年约有68000人受到JE的影响,导致大量死亡和残疾,特别是在亚太地区.
研究的目的:
- 提供关于具有潜在抗JEV活性的生物活性天然产品的研究和开发的全面概述.
- 为了突出新型抗JEV疗法的迫切需要,由于目前的疫苗的局限性和没有批准的药物.
主要方法:
- 对已报告具有抗JEV特性的天然产品的文献综述.
- 对已识别的生物活性天然产品的来源,结构和有效性的分析.
主要成果:
- 自然产品为药物开发提供多样化的来源,独特的化学结构和成本效益.
- 本综述整合了当前关于天然化合物的研究,研究了它们对抗JEV感染的潜力.
结论:
- 自然产品是开发新抗JEV药物的重要和未被充分探索的资源.
- 对天然产品衍生疗法的进一步研究对于有效的JEV控制和预防至关重要.
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