尽管早期的表皮质化,但高层隔膜封闭的双心血栓在高层隔膜封闭
Christopher Herron1,2, Karen Iacono3, David Nykanen3
1Department of Pediatric Cardiology, Arnold Palmer Hospital for Children, Orlando, FL, USA. christopher.herron@orlandohealth.com.
Pediatric cardiology
|September 24, 2024
概括
在心房隔膜缺陷 (ASD) 和孔膜 (PFO) 关闭中,与设备相关的血栓是罕见的. 一个年轻女性患有PFO关闭后复发性血栓的病例凸显了更新临床指南的必要性.
科学领域:
- 心脏病学 心脏病学
- 干预心脏病学 干预心脏病学
- 血栓形成的原因之一是血栓形成.
背景情况:
- 与设备相关的血栓 (DRT) 是心房隔膜缺陷 (ASD) 和孔膜 (PFO) 设备关闭后的不常见并发症.
- 风险因素DRT包括心房动,高凝血状态,和不充分的设备内皮质化.
研究的目的:
- 在年轻患者中,在PFO设备关闭后,呈现一次复发性双心血栓形成的独特案例.
- 突出DRT管理的挑战以及缺乏确定的临床指南.
主要方法:
- 一个15岁的女性病例报告,有脏梗塞史,经过PFO设备关闭.
- 治疗包括抗凝药,抗血小板治疗和间歇性全身组织等离子体激活剂 (tPA).
- 尽管最初的解决方案,但对于持续的血栓而言,该装置的外科实验.
主要成果:
- 患者在PFO关闭3个月后出现了双心血栓.
- 尽管进行了初始治疗,但在初始血栓完全消失后,形成了新的左心房血栓.
- 检测到的装置被发现是完全内皮化,这表明内皮化本身并不能防止复发.
结论:
- 这一案例强调了在ASD/PFO关闭中DRT的不可预测性.
- 缺乏具体的指导方针来管理DRT是一个临床挑战.
- 需要进一步的研究,以建立DRT预防和治疗的最佳实践.
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