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Updated: Jun 12, 2025

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用于制药应用的Olaparib装载固体自纳米乳化药物输送系统 (S-SNEDDS) 的开发和表征

Yuseon Shin1, Mikyung Kim1, Chaeyeon Kim1

  • 1Department of Global Innovative Drugs, The Graduate School of Chung-Ang University, 221 Heukseok-Dong, Dongjak-Gu, Seoul, 06974, Republic of Korea.

AAPS PharmSciTech
|September 24, 2024
PubMed
概括

这项研究开发了一种固体的自纳米乳化药物递送系统 (S-SNEDDS),以提高Olaparib的溶解性和生物可用性. 该S-SNEDDS配方证明了药物释放,稳定性和吸收的增强,为难溶性药物提供了一个有前途的口服输送策略.

关键词:
在 BCS 类 IV 级.生物可用性 生物可用性这就是Olaparib.固体SNEDDS是什么意思喷雾干燥 喷雾干燥

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