相关实验视频

Updated: Jun 12, 2025

Identification of Circular RNAs using RNA Sequencing

Identification of Circular RNAs using RNA Sequencing

Published on: November 14, 2019

[在非小细胞肺癌中循环RNA CircHIPK3的研究进展]

Yuheng Wang¹, Liang Chen¹

¹Department of Thoracic Surgery, First Affiliated Hospital of Nanjing Medical University, Nanjing 210000, China.

Zhongguo fei ai za zhi = Chinese journal of lung cancer

|September 25, 2024

概括

像cirHIPK3这样的循环RNA (circRNAs) 在了解肺癌方面表现有前途. 这篇评论探讨了circHIPK3的情况.

科学领域:

在瘤学瘤学.
分子生物学分子生物学
遗传学是一个遗传学.

背景情况:

肺癌是全球癌症相关死亡的主要原因之一.
循环RNAs (circRNAs) 是稳定的,具有疾病特异性表达的非编码RNA分子.
循环RNAs的失调与包括肺癌在内的各种癌症有关.

研究的目的:

审查循环RNA HIPK3 (circHIPK3) 在非小细胞肺癌 (NSCLC) 中的作用的最新进展.
突出circHIPK3与NSCLC机制,诊断,治疗和预后的关联.
促进肺癌的精确诊断和治疗策略.

主要方法:

关于circHIPK3和NSCLC的最近研究的文献综述.
分析证据,将circHIPK3表达与癌症进展联系起来.
关于circHIPK3在NSCLC发病过程中的作用的综合数据.

主要成果:

circHIPK3是一种致癌性circRNA,与NSCLC的发展有关.
异常表达circHIPK3与NSCLC的进展和患者的结果相关.
circHIPK3显示出作为NSCLC诊断和治疗的生物标志物的潜力.

结论:

circHIPK3在NSCLC的发展和进展中起着重要作用.
准circHIPK3可能为肺癌提供新的治疗策略.
对circHIPK3的进一步研究对于推进肺癌治疗至关重要.

关键词:

生物标志物生物标志物这是循环RNARNA.具有竞争力的内源RNA.这就是HIPK3的原因.肺部瘤是什么肺部瘤

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In Silico Identification and Characterization of circRNAs During Host-Pathogen Interactions

In Silico Identification and Characterization of circRNAs During Host-Pathogen Interactions

Published on: October 21, 2022

Use of Alu Element Containing Minigenes to Analyze Circular RNAs

Use of Alu Element Containing Minigenes to Analyze Circular RNAs

Published on: March 10, 2020

相关概念视频

lncRNA - Long Non-coding RNAs

lncRNA - Long Non-coding RNAs

In humans, more than 80% of the genome gets transcribed. However, only around 2% of the genome codes for proteins. The remaining part produces non-coding RNAs which includes ribosomal RNAs, transfer RNAs, telomerase RNAs, and regulatory RNAs, among other types. A large number of regulatory non-coding RNAs have been classified into two groups depending upon their length – small non-coding RNAs, such as microRNA, which are less than 200 nucleotides in length, and long non-coding RNA...