相关实验视频
Updated: Jun 12, 2025

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A Porcine Model of Acute Autologous Pulmonary Embolism
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急性肺栓塞患者的输管和机械通风:一个范围审查
Eun Sang Lee1,2, Cecilie Dahl Baltsen1,3,4, William B Stubblefield5
1Department of Emergency Medicine, Center for Vascular Emergencies, Massachusetts General Hospital, Boston, MA, USA.
Journal of intensive care medicine
|September 25, 2024
概括
输管过程中的不良事件在高危急性肺栓塞 (PE) 中很常见. 血液动力学崩发生在19% - 28%的患者中,这强调了需要改进的管理策略的需要.
科学领域:
- 关键护理医学 关键护理医学
- 肺部医学 肺部医学
- 心脏病学 心脏病学
背景情况:
- 高危急性肺栓塞 (PE) 具有显著的死亡率.
- 在PE患者中,输管和机械通风可能会加剧心肺呼吸系统的不稳定性.
研究的目的:
- 系统地审查关于急性PE中周管化事件的文献.
- 在急性PE患者中识别与输管相关的不良事件.
主要方法:
- 在多个数据库 (Medline,Embase,Web of Science,CINAHL,Cochrane) 进行系统的文献搜索.
- 两名独立观察员对急性PE中输管和正压通风的研究进行查.
- 数据的综合和偏差风险评估;注册在PROSPERO.
主要成果:
- 包括3项追溯研究,包括104名急性PE患者.
- 在19%-28%的病例中发生了周周输液期间的血液动力学崩.
- 血液动力学崩与心声图右心室 (RV) 功能障碍的更高率有关.
结论:
- 在急性PE中,周周化不良事件很常见.
- 有限的证据需要进一步的研究,以实现最佳管理.
- 改善输管患者的选择对于更好的结果至关重要.
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