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Charlie Yuli Zhang^1,2, Michela Cleri^1,3, Tomas Woodgate^1,4

¹Research Department of Early Life Imaging, School of Biomedical Engineering and Imaging Sciences, King's College London, London, United Kingdom.

Frontiers in pediatrics

|September 25, 2024

概括

低场 (0.55T) MRI 是可行的胎儿心脏成像. 优化的序列弥补了降低的信号噪声比,使得结构的可视化和精确的胎儿血液流量测量.

科学领域:

医疗成像医学成像
心血管成像 - 心血管成像
胎儿医学胎儿医学

背景情况:

临床0.55TMRI扫描仪为胎儿心脏成像提供了潜力.
优化成像序列对于克服低场强度限制至关重要.

研究的目的:

评估0.55TMRI扫描仪用于全面胎儿心脏成像的可行性.
为了优化MRI序列用于胎儿心脏结构和功能评估.

主要方法:

优化平衡稳定状态自由前行 (bSSFP) 和相对比 (PC) 序列使用子宫内研究.
在21个妊娠晚期胎儿中获得了优化的bSSFP,PC和半里叶单射轮回旋回声 (HASTE) 序列.
在静脉,下降性大动脉和上腔静脉中使用PC序列和回顾性关门进行血液流量测量.

主要成果:

优化的bSSFP序列显示SNR增加了1.6倍,并在0.55T时改善了对比度.
PC序列实现了SNR的增加和缩短扫描时间,使得血液流量测量成功.
重建和大血管细分的质量很好,胎儿心脏结构和血管始终可视化.

结论:

0.55T MRI 是胎儿心脏检查的一个可行的选择.
对序列参数的战略优化有效地弥补了在低场强度下降的SNR.
该研究证明了低场MRI用于胎儿心脏成像的稳定性和可重复性.

关键词:

血液流量测量血液流量测量遗传性心脏病是一种先天性心脏病.胎儿心脏病胎儿心脏病胎儿成像检查胎儿成像检查低距离的低场运动.磁共振成像技术的使用

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Magnetic Resonance Imaging

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