试管肺:一个机械试管肺,具有可配置的气道阻力,肺弹性和呼吸力
Wei Yang Tay1, Christopher Yew Shuen Ang1, Yeong Shiong Chiew1,2
1Monash University Malaysia, Jalan Lagoon Selatan, Bandar Sunway, 47500 Subang Jaya, Selangor, Malaysia.
HardwareX
|September 25, 2024
概括
一个新的,负担得起的机械试验肺精确模拟患者的呼吸,有助于优化机械通风设置. 这种可访问的工具增强了患者的护理,并支持了先进的生理模型的开发.
科学领域:
- 生物医学工程 生物医学工程
- 呼吸系统生理学 呼吸系统生理学
- 医疗器械 医疗器械
背景情况:
- 机械通风 (MV) 需要精确的设置,因为患者的变化而具有挑战性.
- 目前的机械试验肺通常是昂贵和难以获得的,限制了它们的临床使用.
- 优化MV设置对于患者的治疗结果至关重要,但很难用现有的工具实现.
研究的目的:
- 设计和制造一个可复制,具有成本效益的机械试验肺.
- 为个别患者提供一个试验各种MV设置的平台.
- 为了解决对当前临床试验肺部负担得起的替代品的需求.
主要方法:
- 设计和建造3个子系统的机械试验肺 (肺区,呼吸道,自发呼吸系统) 的详细说明.
- 测试设备复制临床现实的肺弹性和气道阻力值的能力.
- 模拟自发呼吸模式,并将通风数据与经过认证的临床试验肺部进行比较.
主要成果:
- 试验肺复制了临床现实的肺弹性 (25-85 cmH2O/L) 和气道阻力 (10-45 cmH2O·s/L).
- 它成功地模拟了各种自发的呼吸模式.
- 生成的压力和流量数据可与经过认证的临床试验肺部在各种场景中进行比较.
结论:
- 开发的机械试验肺是优化机械通风的多功能和可访问的工具.
- 它为改善患者护理和推进生理学建模提供了宝贵的机会.
- 这种具有成本效益的设备可以促进更好的方法来识别最佳的通风器设置.
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