在咳中心接受治疗的成年人中,耐火和无法解释的慢性咳的患病率
Paweł Kukiełka1,2, Katarzyna Moliszewska1,2, Katarzyna Białek-Gosk3
1Student's Scientific Group "Alveolus", Medical University of Warsaw, Warsaw, Poland.
ERJ open research
|September 25, 2024
概括
难治性慢性咳在寻求专门护理的患者中很常见,在咳诊所评估的患者中,超过30%的人受到影响. 准确地定义这种情况对于准确的诊断和有效的治疗策略至关重要.
科学领域:
- 肺部病理学 肺部病理学
- 临床医学 临床医学
背景情况:
- 耐火性慢性咳和无法解释的慢性咳带来了重大的临床挑战,并影响了患者的生活质量.
- 目前缺乏对耐火性慢性咳的准确定义.
- 这项研究解决了在定义和识别耐火性慢性咳方面需要明确的需求.
研究的目的:
- 为了确定耐火性慢性咳和无法解释的慢性咳在被转诊到专门的咳中心的患者中的患病率.
- 分析不同诊断标准如何影响耐火性慢性咳的患病率.
主要方法:
- 一项前性队列研究对2018年至2022年在咳诊所诊断的患者进行.
- 用视觉模拟尺度 (VAS) 评估咳严重程度和莱斯特咳问卷 (LCQ) 评估生活质量来评估治疗反应.
- 耐药性慢性咳被定义为持续的严重咳 (VAS ≥40/100毫米),在至少两次治疗尝试后,最少有改善 (VAS变化<30毫米).
主要成果:
- 在201名患者中,只有1.5%被诊断患有无法解释的慢性咳.
- 在166名患者中,30.7%符合基于初级定义的耐火性慢性咳标准.
- 应用更严格的标准导致耐火性慢性咳的患病率为27.1%.
结论:
- 耐火性慢性咳在参加咳诊所的患者中非常普遍.
- 耐火性慢性咳的患病率根据使用的诊断标准略有变化.
- 澄清耐火性慢性咳的定义对于一致的临床实践至关重要.
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