韩国和美国亚洲人群中估计的GFR使用2021年基于肌的GFR估计方程,不包括种族
Jimin Hwang1,2, Kwanghyun Kim3,4,5,6, Josef Coresh2,7
1Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, TX.
Kidney medicine
|September 25, 2024
概括
2021年慢性病流行病学协作 (CKD-EPI) 方程式略有降低了亚洲人群中慢性病 (CKD) 患病率估计. 这种变化显著地重新分类了G3-5.5阶段CKD的个体.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學專業.
- 流行病学 流行病学
- 公共卫生 公共卫生
背景情况:
- 2021年CKD-EPI方程更新了基于肌的eGFR,删除了种族系数.
- 以前的CKD-EPI方程开发涉及有限的亚洲参与者数据.
- 新方程式对亚洲人群中CKD患病率的影响需要进行调查.
研究的目的:
- 用2009年和2021年的CKD-EPI肌素方程来比较CKD患病率估计.
- 根据亚洲人口中的新方程式,评估CKD G3+病例的重新分类.
主要方法:
- 这是一项观察性研究,利用了来自两个国家健康调查的数据.
- 包括2019年韩国国家健康和营养调查的参与者.
- 包括自报的亚洲参与者从美国国家健康和营养调查 (2011-2020) 中.
主要成果:
- 2021年CKD-EPI等式显示CKD患病率略有下降:韩国人的9.75%和美国亚洲人的11.60%.
- 与2009年同期相比,韩国人的患病率下降了0.63%,美国亚洲人的患病率下降了0.84%.
- 发生了显著的重新分类:32.8%的韩国人和30.2%的美国亚洲人患有CKD G3-5不再使用2021年方程被归类为CKD.
结论:
- 2021年CKD-EPI肌素方程结果显示,韩国和美国亚洲人群中CKD患病率略有降低.
- 这种流行率下降的幅度在两个亚洲群体之间是相似的.
- 根据更新的方程,相当一部分中度至重度CKD (G3-5) 患者被重新分类为较低CKD阶段.
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