儿童的QT间隔与静止失调:站立负荷的变化
Miho Sakata1,2, Yoshinobu Oyazato1, Atsushi Nishiyama1
1Department of Pediatrics, Kakogawa Central City Hospital, Kakogawa, Hyogo, Japan.
Pediatrics international : official journal of the Japan Pediatric Society
|September 25, 2024
概括
与没有OD的儿童相比,患有正静止失调 (OD) 的儿童在站立时表现出明显增加的纠正QT间隔 (QTc). 更高的QTc可能有助于诊断儿科患者的OD.
科学领域:
- 心脏病学 心脏病学
- 儿科 儿科 儿科
- 自主神经系统功能 自主神经系统功能
背景情况:
- 纠正的QT间隔 (QTc) 受自主神经系统活动的影响.
- 静态失调 (OD) 是一种影响自主调节的疾病.
- 之前的研究表明,QTc和交感静脉平衡之间存在联系.
研究的目的:
- 为了调查被诊断患有正静止失调 (OD) 的儿童是否在站立时表现出延长的正确QT间隔 (QTc).
- 为了比较OD和没有OD的儿童之间站立的QTc测量.
主要方法:
- 对接受了Schellong测试和心电图的患者进行了回顾性分析.
- 根据日本青少年OD临床指南将患者分为OD阳性和OD阴性组.
- 在基线和站立后评估心率,QT间隔和QTc.
主要成果:
- 与OD阴性组 (52名患者) 相比,OD阳性组 (73名患者) 的心率增加显著更高,QT间隔在站立时缩短更大.
- 从基线到站立的修正QT间隔 (QTc) 的变化在OD阳性组中明显明显.
- 在两组中,QTc从基线显著增加到常态,OD阳性组的QTc幅度更大.
结论:
- 校正的QT间隔 (QTc) 显示,与基线相比,在患有正静失调 (OD) 的儿童中,从站立到站立的时间显著增加.
- 站立时QTc值升高可能成为儿童群体OD诊断的有价值的辅助标记.
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