发生突发胆囊切除术的细菌病患者的发病率增加和出院后的一年死亡率:一项探索性回顾性观察性研究
Melissa L Harry1, Kristin P Colling2, Kassandra Dindinger-Hill3
1Essentia Institute of Rural Health, Essentia Health, Duluth, Minnesota, USA.
Surgical infections
|September 25, 2024
概括
在新出现的胆囊切除术期间很少进行血培养,但积极的结果表明败血症的风险更高,住院时间更长,死亡率增加. 实施协议可以改善患者的治疗结果.
科学领域:
- 外科手术的结果
- 传染病流行病学 传染病流行病学
- 胆囊疾病研究研究 胆囊疾病研究
背景情况:
- 胆囊疾病很常见,从胆结石到严重的胆管炎.
- 关于新出现的胆囊切除术患者的细菌病率的研究有限.
- 阳性血液培养可能表明患者的结果更差.
研究的目的:
- 为了确定血液培养在新兴胆囊切除术中的频率.
- 调查阳性血液培养物与患者结果之间的关联.
- 为了确定阳性血液培养的危险因素.
主要方法:
- 追溯观察队列研究 (2011-2018).
- 包括892名接受新兴胆囊切除术的患者.
- 使用统计方法分析血液培养数据,患者人口统计数据和结果.
主要成果:
- 只有16.2%的患者获得了血液培养;其中22.8%的结果呈阳性.
- 阳性血液培养与年龄较大,败血症发病率较高,住院时间较长,一年死亡率增加 (18.2%对6.3%) 相关联.
- 在4.5%的新出现的胆囊切除术中诊断出胆囊炎;大肠杆菌是最常见的隔离物.
结论:
- 新兴胆囊切除术患者的阳性血液培养与明显更差的结果有关.
- 常规血液培养方案可能有助于识别高风险患者.
- 进一步的研究可以完善这种人群中细菌病的管理策略.
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