女同性恋,男同性恋和双性恋者的精神病风险:系统性审查和元分析
Jean-Paul Selten1, Hussam Alrashed2,3, Hans Oh4
1Department of Psychiatry and Neuropsychology, Faculty of Health, Medicine, and Life Sciences, Mental Health and Neuroscience Research Institute, Maastricht University, Maastricht, The Netherlands.
Psychological medicine
|September 25, 2024
概括
女同性恋,同性恋,双性恋 (LGB) 个人面临精神病经历和障碍的风险增加,支持社会失败假说. 心理社会压力因素,而不是药物滥用,调解了这种高风险.
科学领域:
- 精神病学是一个精神病学.
- 社会心理学 社会心理学
- 流行病学 流行病学
背景情况:
- 社会失败假说将低社会地位和羞辱与精神病障碍 (PDs) 和精神病经历 (PE) 的风险增加联系在一起.
- 女同性恋,男同性恋或双性恋 (LGB) 个人可能会经历独特的社会压力因素,这可能会增加他们患PD和PEs的风险.
研究的目的:
- 系统地审查和定量综合研究,检查LGB个人中PD和PEs的风险.
- 评估LGB身份是否与PD和PEs风险增加有关.
主要方法:
- 在PubMed,PsycINFO,Embase和Web of Science数据库中进行系统搜索.
- 两个独立的审查者评估了研究的资格和质量,提取了数据,并使用随机效应模型分析了效应大小.
- 聚合赔率比率 (ORs) 计算了PDs和PEs,有和没有共变量调整.
主要成果:
- 在排除了一项低质量的研究后,LGB个人对PD的整合几率比率显著增加 (未调整的OR=2.77,调整的OR=2.67).
- 对于LGB个人来说,PEs的聚合概率比率显著增加 (未调整的OR=1.97,调整的OR=1.85).
- 心理社会压力因素,而不是药物滥用,被确定为PEs的关键调解者;父母的支持在青少年中显示出保护作用.
结论:
- 研究结果表明,LGB人群患精神病的风险较高,符合社会失败假说.
- 结果强调了社会逆境和歧视对LGB人群心理健康结果的影响.
- 进一步的研究应该探索危险LGB个体的保护因素和有针对性的干预措施.
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