对患有神经障碍的成年人抑郁和焦虑的认知行为干预:系统性审查和元分析
Milena Gandy1, Thomas Woldhuis1, Wendy Wu1
1School of Psychological Sciences, Macquarie University, Sydney, Australia.
Psychological medicine
|September 25, 2024
概括
认知和行为干预显著改善了神经系统疾病的成年人的抑郁和焦虑症状. 这些疗法在各种疾病中提供小到中等的益处,增强患者的幸福感.
科学领域:
- 神经科学是一个神经科学.
- 精神病学是一个精神病学.
- 临床心理学 临床心理学
背景情况:
- 抑郁和焦虑在患有神经系统疾病的成年人中很普遍,影响生活质量.
- 需要有效的干预措施来管理这些并发性心理症状.
研究的目的:
- 系统评估认知和行为干预措施对患有神经障碍的成年人抑郁和焦虑的疗效.
- 使用元分析综合随机对照试验 (RCT) 的发现.
主要方法:
- 在多个数据库 (Cochrane,MEDLINE,PsycINFO,Embase,Neurobite) 进行了全面的系统搜索,截至2024年5月.
- 包括涉及神经疾病和抑郁/焦虑症的成年人的随机对照试验 (RCT).
- 随机效应元分析被用来为抑郁症和焦虑症症状变化结合效应大小 (Hedges' g).
主要成果:
- 分析了54个RCT,其中有5372名参与者,涉及11种神经疾病.
- 与对照组相比,干预结果显示抑郁症 (g = 0.45) 和焦虑症 (g = 0.38) 症状显著改善.
- 通过最低基线症状严重性标准和非活性对照 (抑郁症) 提高了疗效.
结论:
- 认知和行为干预措施在患有神经疾病的成年人中为抑郁和焦虑提供了小到中等的统计学上显著的好处.
- 效果因神经系统疾病类型和结果量度而异,这表明定制方法可能是有益的.
- 进一步的研究可以探索针对特定神经病群体的最佳干预策略.
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