在患有自身免疫性疾病的患者中,肺癌手术后的生存率
Masaaki Nagano1, Yue Cong2, Keita Nakao2
1Department of Thoracic Surgery, The University of Tokyo Graduate School of Medicine, 7-3-1 Hongo, Bunkyo-Ku, Tokyo, 113-8655, Japan. managano-tky@umin.ac.jp.
Surgery today
|September 25, 2024
概括
接受肺癌手术的自身免疫性疾病患者的短期结果类似,但长期生存率更差. 密切监测对于这些患者在手术后至关重要.
科学领域:
- 在瘤学瘤学.
- 免疫学 免疫学 免疫学
- 外科手术的结果
背景情况:
- 自身免疫性疾病 (ADs) 增加肺癌风险,但可能影响瘤免疫力.
- 了解ADS对肺癌手术结果的影响至关重要.
研究的目的:
- 为了评估自身免疫性疾病 (ADs) 对手术结果和肺癌手术后生存的影响.
主要方法:
- 对1236名非小细胞肺癌患者 (2007-2018) 的回顾性审查.
- 在患有和没有ADS的患者之间比较术后和长期结局.
- 倾向性得分匹配用于队列平衡 (114对).
主要成果:
- 在患有和没有ADS的患者之间,术后结果没有显著差异.
- 在ADS患者中,整体存活率显著降低.
- 在ADS患者中,无复发生存率显著降低.
结论:
- 肺癌手术在没有增加术后并发症的AD患者中是可行的.
- 患有AD的患者在肺癌手术后的长期存活率明显降低.
- 对于患有肺癌的AD患者,建议加强监测和全面检查.
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