在中国老年人中暴露于多重金属和高血压
Rui Zhang1, JiaMou Zhou2, PengCheng Huo2,3
1Hefei Stomatological Hospital, Hefei, Anhui Province, China.
Biological trace element research
|September 25, 2024
概括
在中国老年人中,和的暴露与高血压风险较高有关. 减少接触这些金属可能有助于预防高血压,特别是对于糖尿病患者.
科学领域:
- 环境健康 环境健康
- 心血管健康 心血管健康
- 毒理学 毒理学 毒理学
背景情况:
- 关于金属化物对成年人高血压的影响的证据有限.
- 高血压是一个重要的公共卫生问题,特别是在老年人群中.
研究的目的:
- 评估七种选定的金属化物 (,,,,,,,) 与中国老年人的高血压之间的单个和联合关联.
- 调查金属化物混合物在这个人口群体中高血压发展中的作用.
主要方法:
- 一项涉及1009名中国老年人的研究.
- 测量了7种金属化物在血液中的度,使用诱导合血质谱法 (ICP-MS).
- 高血压是由血压值,自我报告或药物使用来定义的. 后勤回归和贝叶斯内核机器回归 (BKMR) 用于分析.
主要成果:
- (Pb) 显示出与高血压有显著的积极关联,无论是单独的还是在多金属 () 模型中.
- 金属 (?? 化物) 混合物与高血压有积极的关联,具有最高的后部入概率.
- 观察到和 (Mn) 之间对高血压的多重相互作用,以及和对其他金属 (loid) 协会的添加效应.
结论:
- 暴露于金属 (化物) 混合物可能会导致中国老年人的高血压,主要是由及其与的相互作用驱动的.
- 减少和的暴露可能是预防老年人高血压的策略,尤其是糖尿病患者.
- 金属化物和高血压之间的关联受糖尿病,地理区域,年龄和体重指数 (BMI) 等因素的影响.
关键词:
BKMR BKMR 在线播放在高血压的高血压.金属 (化物) 的类型年龄较大的成年人.Pb Pb Pb Pb Pb Pb Pb Pb Pb Pb Pb Pb Pb Pb Pb Pb Pb Pb Pb Pb Pb Pb Pb Pb Pb更多相关视频
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