微小和纳米ZnO颗粒对L.小的有毒作用的差异 - - 综合性方法
Sandra Radić Brkanac1, Ana-Marija Domijan2, Petra Peharec Štefanić1
1Faculty of Science, Department of Biology, University of Zagreb, 10000, Zagreb, Croatia.
Environmental science and pollution research international
|September 25, 2024
概括
纳米尺寸的氧化颗粒 (nZnO) 对比微型颗粒 (mZnO) 更有毒. nZnO 破坏光合作用,并因增加吸收而导致更大的氧化应激和DNA损伤.
科学领域:
- 环境科学 环境科学
- 植物生物学 植物生物学
- 毒理学 毒理学 毒理学
背景情况:
- 氧化纳米颗粒 (nZnO) 的使用越来越多,引发了人们对其环境影响的担忧.
- 了解纳米与微型颗粒的毒性差异对于风险评估至关重要.
研究的目的:
- 为了比较nZnO和微型ZnO (mZnO) 在草 (Lemna minor) 中的毒性.
- 阐明粒子毒性背后的机制,重点关注氧化应激和基因毒性.
主要方法:
- 草被暴露在不同度的nZnO和mZnO中长达7天.
- 评估的关键参数包括生长速度,光合作用,氧化应激标志物和基因毒性.
主要成果:
- nZnO和mZnO都表现出植物毒性,主要是通过离子释放.
- 与mZnO相比,nZnO导致植物中的积累显著增加,并引起更严重的氧化应激,光合作用障碍和DNA损伤.
- 多变量分析表明,nZnO毒性机制涉及光合作用反应的破坏,通过因增强吸收而引起的氧化还原失衡来破坏光合作用反应.
结论:
- nZnO对水生植物的毒理风险比mZnO更大.
- 增强的nZnO毒性与的摄入量增加以及随后的细胞氧化还原平衡和光合作用过程的破坏有关.
相关概念视频
Toxic Reactions: Overview
When toxic substances penetrate the human body, they disseminate to various tissues, undergoing metabolic changes. This process yields reactive metabolites that may covalently bind with specific target molecules, resulting in toxicity.
Toxicity falls into two primary categories: local and systemic.
Local toxicity appears at the exposure site, such as protein denaturation caused by caustic substances.
In contrast, systemic toxicity requires the toxic agent's absorption and distribution,...
Toxicity falls into two primary categories: local and systemic.
Local toxicity appears at the exposure site, such as protein denaturation caused by caustic substances.
In contrast, systemic toxicity requires the toxic agent's absorption and distribution,...
Microbial Corrosion
Microbiologically Influenced Corrosion (MIC) is a significant form of material degradation caused by the metabolic activities of microorganisms. This phenomenon poses substantial challenges across various industries, including oil and gas, maritime, and water treatment sectors.MIC occurs when microorganisms, such as bacteria, archaea, and fungi, colonize metal surfaces, forming biofilms that alter the local electrochemical environment. These biofilms can lead to the production of corrosive...


