左心室辅助器械的临床结果 血流并发症
Shusuke Imaoka1, Daisuke Yoshioka1, Shunsuke Saito1
1From the Department of Cardiovascular Surgery, Osaka University Graduate School of Medicine, Suita Shi, Osaka Fu, Japan.
概括
高血压指标,如脚脉冲波速和系统血管阻力升高,与左心室辅助器件 (LVAD) 患者的出血并发症有关. 动脉样硬化可能会增加LVAD植入后的出血风险.
科学领域:
- 心脏病学 心脏病学
- 医疗器械 医疗器械
- 血管生物学 血管生物学
背景情况:
- 出血并发症是患有左心室辅助器件 (LVAD) 的患者发病和死亡的重要原因.
- 在LVAD植入后的血液动力学因素可能会影响出血风险.
研究的目的:
- 为了研究血液动力学参数和LVAD植入后出血并发症之间的关联.
- 在LVAD接受者中识别出出血的潜在风险因素.
主要方法:
- 78名接受了连续流动LVAD植入物和血液动力学坡道测试的患者的回顾性评估.
- 分析手术前的平均臂脉冲波速 (baPWV) 和植入后的全身血管阻力 (SVR).
主要成果:
- 在13名患者中发生出血并发症,胃肠道出血是最常见的.
- 较高的手术前baPWV (1,276±280对1,098±190厘米/秒,p=0.04) 与出血有关.
- 在血液动力学测试期间,在患有出血并发症的患者中观察到升高的SVR (1,359±341对1,150±217 dyne sec/cm5,p=0.01).
结论:
- 术前高的baPWV和植入后高的SVR与LVAD植入后的出血并发症显著相关.
- 高baPWV表示的动脉样硬化是LVAD患者出血并发症的危险因素.
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