前列腺癌遗传检测现行做法:印度情景
Ganesh Bakshi1, Senthil Rajappa2, Amit Joshi3
1Uro-oncologist, P. D. Hinduja Hospital and Medical Research Centre, Mumbai, Maharashtra, India.
Indian journal of public health
|September 25, 2024
概括
在印度,前列腺癌 (PCa) 的基因检测尚未得到充分利用,同类重组修复 (HRR) 基因的处方率较低. 提高可负担性和获得测试和向治疗的机会对于个性化PCa护理至关重要.
科学领域:
- 在瘤学瘤学.
- 遗传学 遗传学 是一个
- 医学实践 医学实践
背景情况:
- 国际指导方针建议在前列腺癌 (PCa) 中进行基因测试以选择向治疗.
- 关于目前印度PCa遗传检测实践的数据有限.
研究的目的:
- 调查印度前列腺癌 (PCa) 遗传检测的当前模式.
- 在PCa管理中确定基因测试的障碍和促进者.
主要方法:
- 一份经过验证的在线问卷被分发给印度各地的瘤学家和泌尿瘤学家.
- 数据从2022年2月到5月收集,并使用描述性统计数据分析了响应.
主要成果:
- 只有35.9%的参与者建议在不到5%的PCa患者中进行基因检测.
- 同类重组修复 (HRR) 基因检测是50.2%的常规检测,血液和组织是首选样本.
- 主要障碍包括成本和遗传咨询师的缺乏;成本效益和改善药物获取被确定为解决方案.
结论:
- 在印度各地观察到对HRR基因进行基因测试的频率较低.
- 提高基因测试和向治疗的质量,可访问性和成本效益对于个性化转移性PCa护理至关重要.
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