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基于家庭的跨直流刺激与营养咨询治疗对暴饮暴食障碍症状的影响:一项随机试点试验
Jessica Lorenzzi Elkfury1, Luciana C Antunes2, Betina Franceschini Tocchetto1
1Post-Graduate Program in Medical Sciences, School of Medicine, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil. Laboratory of Pain and Neuromodulation, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil.
概括
营养咨询疗法 (NCT) 结合跨直流刺激 (tDCS) 并没有协同减少暴饮暴食障碍 (BED) 的症状. 然而,随着时间的推移,BED症状减少,在活跃的tDCS组中,抑制功能得到改善.
科学领域:
- 神经科学是一个神经科学.
- 精神病学是一个精神病学.
- 临床心理学 临床心理学
背景情况:
- 暴饮暴食障碍 (BED) 是一种普遍存在的饮食障碍,其特点是经常出现过度饮食.
- 目前用于BED的治疗方法,包括营养咨询疗法 (NCT),表现出不同的疗效.
- 超直流刺激 (tDCS) 是一种新兴的神经调节技术,具有潜在的治疗应用.
研究的目的:
- 调查NCT和tDCS对BED症状的综合影响.
- 评估与NCT一起使用的活性tDCS (a-tDCS) 与假装tDCS (s-tDCS) 的影响.
主要方法:
- 一个随机对照试验,涉及40名被诊断患有BED的妇女.
- 参与者被分配为使用a-tDCS进行NCT,使用s-tDCS进行NCT或单独使用NCT.
- 基于家庭的tDCS在背侧前额叶皮层上进行了28次治疗.
主要成果:
- 结合NCT和tDCS对BED症状没有显著的协同效应.
- 随着时间的推移,在所有组中都出现了BED症状的显著减少,这种症状是通过Binge Eating Scale测量的.
- 短间隔皮质内抑制 (SICI) 是神经抑制的标志物,在a-tDCS组中增加.
结论:
- 在这项试点研究中,NCT和tDCS的组合没有显示出对BED症状减少的协同效应.
- 虽然没有协同作用,但tDCS可能会影响与BED相关的神经抑制过程.
- 需要进一步的大规模研究,以探索tDCS与行为干预相结合的潜力,以治疗BED.
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