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相关概念视频

Teeth01:15

Teeth

352
The formation of teeth, also known as odontogenesis, is a complex process that begins in utero, around the sixth week of embryonic development. There are three stages to this process: the bud stage, the cap stage, and the bell stage.
In the bud stage, the tooth germ (an aggregation of cells) starts to form in the developing jawbone. During the cap stage, the tooth germ differentiates into enamel organ, dental papilla, and dental sac, which will later develop into the tooth's enamel, dentin...
352
Tooth Anatomy01:21

Tooth Anatomy

391
The human tooth enables us to eat a variety of foods, speak clearly, and even aid in shaping our faces. Teeth are composed of various elements that work together. Here's a detailed look at the anatomy of a human tooth.
The Crown, Neck, and Root
The visible part of the tooth is referred to as the crown. It's covered by enamel, the hardest substance in the human body. The crown is uniquely shaped for each type of tooth, allowing for different functions such as cutting, tearing, or...
391
Minerals01:26

Minerals

289
Minerals are essential nutrients that the human body needs in small amounts to work properly. They play a vital role in many bodily functions, such as building strong bones and transmitting nerve impulses. Some minerals are needed for hormone production or to maintain a normal heartbeat. Major minerals include calcium, phosphorus, potassium, sulfur, sodium, chlorine, and magnesium, while trace minerals include iron, manganese, copper, iodine, zinc, cobalt, fluoride, and selenium.
 
Major...
289
Bone Disorders01:29

Bone Disorders

3.4K
Aging and its effect on bone remodeling is the most common cause of bone disorders. In young and healthy people, bone deposition and resorption happen at an equal rate to maintain optimal bone health.
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
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Teratogenicity01:07

Teratogenicity

2.4K
The ability of a drug to produce structural deformations and functional abnormalities in the developing embryo or the fetus is called teratogenicity, and the drug producing this effect is known as a teratogen. Teratogenic effects include stillbirth, miscarriage, intrauterine growth restriction, and neurocognitive delay. A teratogen may affect the embryo at different stages of development, which is important in determining the type and extent of the damage. During blastocyst formation, the early...
2.4K
Essential Minerals for Bone Health01:31

Essential Minerals for Bone Health

3.8K
The minerals contained in all of the food we consume are essential for our organ systems. However, certain essential minerals, such as calcium, phosphorus, magnesium, manganese, and fluoride, largely affect bone health.
Calcium and Phosphorus
Calcium is a critical component of bones, especially in the form of calcium phosphate and calcium carbonate. Since the body cannot make calcium, it must be obtained from the diet. However, calcium cannot be absorbed from the small intestine without...
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相关实验视频

Updated: Jun 12, 2025

Micro-dissection of Enamel Organ from Mandibular Incisor of Rats Exposed to Environmental Toxicants
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乳的发育缺陷 乳的发展缺陷

Daiana da Silva Martins1, Franciny Querobim Ionta1,2, Gustavo Pompermaier Garlet3

  • 1Department of Pediatric Dentistry, Orthodontics and Public Health, Bauru School of Dentistry, University of São Paulo, Bauru, Brazil.

Monographs in oral science
|September 25, 2024
PubMed
概括

牙面膜发育缺陷 (DDE) 源于牙形成过程中出现的问题,影响牙的形成. 了解这些缺陷,比如切口的低矿化 (MIH) 和非完美的乳腺发育 (AI),对于诊断和管理至关重要.

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Development of Amelogenin-chitosan Hydrogel for In Vitro Enamel Regrowth with a Dense Interface
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科学领域:

  • 牙科科学 牙科科学
  • 发展生物学 发展生物学
  • 遗传学 是一个遗传学.

背景情况:

  • 乳液形成的过程 - - 乳液形成过程 - - 可因遗传,系统和环境因素而受到干扰.
  • 这些干扰导致了牙的各种发育缺陷 (DDE),包括切口的低矿化 (MIH),牙的低化,牙的化,以及不完美的牙发育 (AI).

研究的目的:

  • 为了提供一个全面的概述 amelogenesis 和 DDE.
  • 为了将组织病理学发现与DDE的临床表现相关联.
  • 突出每个DDE类型的诊断挑战和病因因素.

主要方法:

  • 关于乳腺生成和DDE的文献综述.
  • 对MIH,牙面膜低成形,牙光症和AI的组织病理和临床特征的分析.
  • 讨论与AI相关的遗传突变.

主要成果:

  • MIH是一种影响矿化/成熟的质性缺陷,由于严重程度和影响的变化,它存在诊断挑战.
  • 乳低成形是一种定量缺陷,受母体分泌过程中病因因素的时间影响.
  • 牙化是化物毒性影响乳腺细胞的结果,而AI包括与特定基因突变相关的多种表型的遗传性牙缺陷.

结论:

  • 准确的DDE诊断,包括MIH,牙质低成形,牙化和AI,对于有效的临床管理至关重要.
  • 了解影响乳腺发育的因素的复杂相互作用是解决这些发育缺陷的关键.