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Updated: Jun 12, 2025

Combining Mitotic Cell Synchronization and High Resolution Confocal Microscopy to Study the Role of Multifunctional Cell Cycle Proteins During Mitosis
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Published on: December 5, 2017

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通过CDK5RAP2部分关闭γ-tubulin环复合体,激活了微管细胞核化

Yixin Xu1, Hugo Muñoz-Hernández1, Rościsław Krutyhołowa1

  • 1Department of Biology, Institute of Molecular Biology and Biophysics, ETH Zürich, 8093 Zürich, Switzerland.

Developmental cell
|September 25, 2024
PubMed
概括

由于其结构,马管素环复合体 (γ-TuRC) 很难核化微管. 这项研究揭示了CDK5RAP2结合如何诱导γ-TuRC的结构变化,增强微管核形成.

关键词:
在CDK5RAP2中使用CDK5RAP2.中心体 中心体 中心体 中心体低温电磁波冷却器 (Cryo-EM) 是一个非常好的方法.微管细胞核化的过程微管是微管的组成部分.γ-氨酸环复合体 γ-氨酸环复合体

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