相关实验视频

Updated: Jun 12, 2025

Metabolic Glycoengineering of Sialic Acid Using N-acyl-modified Mannosamines
12:06

Metabolic Glycoengineering of Sialic Acid Using N-acyl-modified Mannosamines

Published on: November 25, 2017

12.7K

哺乳动物酸乙酶的结构分析

Danilo Ide1, Alexei Gorelik1, Katalin Illes1

  • 1Department of Biochemistry and Centre de Recherche en Biologie Structurale (CRBS), McGill University, Montreal, QC H3G 0B1, Canada.

Journal of molecular biology
|September 25, 2024
PubMed
概括

酸乙酶 (SIAE) 调节细胞过程,与自身免疫性疾病有关. 结构研究揭示了其催化机制和广泛的基质特异性,为新疗法提供了洞察力.

关键词:
通过O-乙化.美国国家航空公司SIAE在X射线晶体学.分子动力学分子动力学酸乙酶是酸乙酶的一种.

更多相关视频

Determination of Sialic Acids in Liver and Milk Samples of Wild-type and CMAH Knock-out Mice.08:04

Determination of Sialic Acids in Liver and Milk Samples of Wild-type and CMAH Knock-out Mice.

Published on: July 14, 2017

9.7K
Visualizing Intracellular Sialylation with Click Chemistry and Expansion Microscopy08:16

Visualizing Intracellular Sialylation with Click Chemistry and Expansion Microscopy

Published on: February 7, 2025

390

相关概念视频

Oligosaccharide Assembly01:24

Oligosaccharide Assembly

Protein glycosylation starts in the ER lumen and continues in the Golgi apparatus. Glycosyltransferases catalyze the addition of sugar molecules or glycosylation of proteins. Usually, these enzymes add sugars to the hydroxyl groups of selected serine or threonine residues to form O-linked glycans or the amino groups of asparagine residues to form N-linked glycans. Different positions on the same polypeptide chain can contain differently linked glycans.
Multiple sugar molecules that may or may...
2.8K