肺功能和睡眠障碍症状之间的关联在一个基于社区的多站点病例调查研究中
Rosetta Mazzola1, Shawn D Aaron1,2, Katherine L Vandemheen2
1Department of Medicine, Faculty of Medicine, University of Ottawa, Ottawa, Ontario, Canada.
Journal of sleep research
|September 25, 2024
概括
未诊断的喘与失眠有关,呼吸系统症状与成人睡眠障碍相关. 在这项研究中,肺功能测量没有显示出与睡眠问题的直接联系.
科学领域:
- 肺部医学 肺部医学
- 睡眠医学 睡眠医学
- 流行病学 流行病学
背景情况:
- 阻塞性呼吸道疾病经常与睡眠障碍有关.
- 早期识别未诊断的肺部疾病对于及时干预至关重要.
- 客观肺功能与主观睡眠质量之间的关系需要进一步研究.
研究的目的:
- 调查肺功能参数与睡眠障碍症状之间的关联.
- 探索未被诊断的阻塞性呼吸道疾病 (慢性阻塞性肺部疾病和喘) 与睡眠障碍之间的联系.
- 检查呼吸系统症状和睡眠症状之间的关系.
主要方法:
- 采用2017年3月至2021年8月的数据进行横截面研究.
- 包括患有呼吸道症状但没有确诊的肺病的参与者,他们完成了螺旋测量和全球睡眠评估问卷.
- 多变量回归模型用于评估螺旋计测量,呼吸道症状 (圣乔治呼吸道问卷,COPD评估测试) 和睡眠症状 (全球睡眠评估问卷) 之间的关联.
主要成果:
- 螺旋计测量 (FEV1,FVC,FEV1/FVC) 与睡眠症状之间没有发现显著的关联.
- 患有未诊断的喘的参与者更有可能报告失眠 (OR 2.58,p=0.02).
- 呼吸道症状与睡眠症状有显著的关联,在报告更多睡眠症状的人群中,在圣乔治呼吸道问卷和COPD评估测试中观察到更高的得分.
结论:
- 在未被诊断的喘和失眠之间存在关联.
- 呼吸系统症状与睡眠障碍症状有关.
- 单独的肺功能参数可能无法完全捕捉阻塞性呼吸道疾病和睡眠障碍之间的关系.
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