在开放式胸腔切除术后慢性术后疼痛的性别差异
Gisela Roca1, Sergi Sabate2, Ancor Serrano3
1Pain Unit, Department of Anesthesiology, Hospital Universitari Germans Trias i Pujol, Universitat Autónoma de Barcelona, Badalona, Spain.
Journal of cardiothoracic and vascular anesthesia
|September 25, 2024
概括
与男性相比,女性在胸切除术后患慢性术后疼痛 (CPSP) 的发生率更高. 这凸显了在手术疼痛研究中考虑性别和性别的必要性.
科学领域:
- 疼痛研究 疼痛研究
- 外科手术的结果
- 性别和性别在健康方面的差异
背景情况:
- 慢性术后疼痛 (CPSP) 是重大手术后的一个重大问题.
- 了解影响CPSP发病率的因素对于改善患者护理至关重要.
- 以前的研究还没有完全阐明胸切除术后CPSP的性别特异性差异.
研究的目的:
- 为了确定在接受开放胸切除术的女性中慢性术后疼痛 (CPSP) 的发生率.
- 为了比较女性和男性之间的患者和程序变量,以确定可能导致CPSP的因素.
- 调查心理措施和手术前疼痛在CPSP基于性别的差异中的作用.
主要方法:
- 在十所大学附属医院进行了观察性队列研究.
- 收集了96名女性和137名预定接受开放胸切除术的男性的数据.
- 记录了疼痛史,心理评估,健康状况,灾难性得分和临床数据,在手术后4个月诊断出CPSP.
主要成果:
- 女性中CPSP的发病率明显高 (53.1%) 与男性相比 (38.0%) (p = 0.023).
- 女性报告了更差的基线心理测量,包括心理状态感知 (p = 0.01),抑郁 (p = 0.006) 和灾难化 (p < 0.001).
- 女性还报告了手术前疼痛增加在手术区域 (p = 0.011) 和其他区域 (p = 0.030).
结论:
- 医生诊断的慢性术后疼痛在胸切除术后的女性中更频繁地发生.
- 性别和性别代表了重要的变量,应该被纳入未来的手术疼痛临床研究.
- 这些发现强调了需要基于性别和性别的方法来治疗手术患者的疼痛.
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