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Updated: Jun 12, 2025

Isolation Protocol of Mouse Monocyte-derived Dendritic Cells and Their Subsequent In Vitro Activation with Tumor Immune Complexes
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抑制MERTK可以选择性地激活DC-T细胞轴,提供抗白血病免疫力

Justus M Huelse1, Swati S Bhasin1, Kristen M Jacobsen1

  • 1Aflac Cancer and Blood Disorders Center, Children's Healthcare of Atlanta and Department of Pediatrics, Emory University, Atlanta, GA, 30322, USA.

Leukemia
|September 25, 2024
PubMed
概括

针对TAM家族激酶MERTK和TYRO3的向显示了B细胞急性白血病 (B-ALL) 免疫治疗的前景. 抑制MERTK或淘汰TYRO3通过增强树突细胞和T细胞来增强抗白血病免疫力.

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