麻风中的头骨神经麻:发表的病例报告和病例系列的系统审查
Ravindra Kumar Garg1, Parul Jain2, Swastika Suvirya3
1Department of Neurology, King George's Medical University, Lucknow, 226003, India. garg50@yahoo.com.
Acta neurologica Belgica
|September 25, 2024
概括
大脑神经参与麻风病通常会影响三角神经和面部神经. 麻风反应可能会引起炎症,但多药疗法 (MDT) 通常可以解决神经影像异常.
科学领域:
- 神经学 神经学
- 传染性疾病 传染性疾病
- 眼科医生 眼科 眼科
背景情况:
- 周围神经的参与在麻风中很常见.
- 病中神经损伤的报道较少,通常是在孤立的案例研究中.
研究的目的:
- 审查麻病中骨神经参与的模式和频谱.
- 为了提高对病的脑神经问题的发病和管理的理解.
主要方法:
- 按照PRISMA指南进行系统审查.
- 在PubMed,Scopus,Embase和谷歌学者中搜索到2024年2月2日.
- 包括病例报告和关于麻风相关的头骨神经干扰的系列.
主要成果:
- 报告了40份关于49名患者的文件 (平均年龄为41.3岁,87.6%是男性).
- 大脑神经受影响最多:面部 (38.8%) 和三角 (28.6%). 多重发生在10.2%的人群中.
- 神经成像显示神经T2/FLAIR高强度/增强延伸到脑干;30%患有麻风反应,51%在治疗后得到改善. 多药疗法 (MDT) 解决了异常.
结论:
- 麻风主要影响三神经和面部神经,有可能导致多重神经.
- 勒普拉反应会引起过度的炎症,影响神经干和/或脑干核.
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