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Updated: Jun 12, 2025

Transmembrane Domain Oligomerization Propensity determined by ToxR Assay
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在受体氨酸激酶中,跨膜域的自发二元化和明显的包装模式

Lev Levintov1, Biswajit Gorai2, Harish Vashisth1,3,4,5

  • 1Department of Chemical Engineering and Bioengineering, University of New Hampshire, Durham, New Hampshire 03824, United States.

Biochemistry
|September 25, 2024
PubMed
概括

胰岛素受体 (IR) 和胰岛素样生长因子-1受体 (IGF1R) 的跨膜域 (TMD) 自发二元化,采用不同的配置. 这种二分化对于理解受体激活机制至关重要.

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