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Updated: Jun 12, 2025

Deciphering the Structural Effects of Activating EGFR Somatic Mutations with Molecular Dynamics Simulation
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解码表观遗传调节器突变对联体受体相互作用干扰的功能影响,用于评估癌症免疫治疗

Aiai Shi1,2,3, Chaohuan Lin1,4, Jie Lyu1,3,5

  • 1Joint Centre of Translational Medicine, Wenzhou Institute, University of Chinese Academy of Sciences, Wenzhou, Zhejiang, People's Republic of China.

Journal of cellular and molecular medicine
|September 26, 2024
PubMed
概括

表观遗传调节器 (ERs) 突变会破坏癌细胞的通信,影响免疫治疗的有效性. 我们的MERIN方法识别了与配体受体相互作用相关的ER突变,有助于癌症治疗的患者分层.

关键词:
癌症 癌症 癌症 癌症 癌症表观遗传调节器是一种表观遗传调节器.免疫系统是免疫系统的.免疫疗法 免疫疗法配体受体相互作用突变是一种突变.

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