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Updated: Jun 12, 2025

Candidate Gene Testing in Clinical Cohort Studies with Multiplexed Genotyping and Mass Spectrometry
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对各种人群构建多基因分数的方法进行比较

Sophia Gunn1, Xin Wang2, Daniel C Posner3

  • 1Biostatistics, Boston University School of Public Health, Boston, MA, USA; VA Boston Healthcare System, Boston, MA, USA.

HGG advances
|September 26, 2024
PubMed
概括

开发多基因分数 (PGSs) 对于不同种群来说至关重要. 结合全基因组关联研究 (GWAS) 数据的多祖先方法与单祖先方法相比,在代表性不足的群体中显著提高了PGS性能.

关键词:
多样化的人口多样化.多基因分数的多基因分数代表性不足的人口.

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