指南,以告知研究人员招聘流程的研究涉及重症患者的研究
Kerry Woolfall1, Katie Paddock2, Megan Watkins3
1Department of Public Health, Policy and Systems, Institute of Population Health, University of Liverpool, Liverpool, UK.
Journal of the Intensive Care Society
|September 26, 2024
概括
在重症监护室 (ICU) 招募重症患者参加临床研究具有挑战性. 这项研究收集了利益相关者的意见,以创建关于ICU研究参与道德和有效的指导方针.
科学领域:
- 医学伦理 医学伦理
- 临床试验 临床试验
- 关键护理医学 关键护理医学
背景情况:
- 在重症监护室 (ICU) 进行临床研究至关重要,但由于患者的危急状况和无法同意,临床研究面临招聘挑战.
- 知情同意通常依赖于亲属或法律代表,他们可能会被压倒,使参与研究的讨论变得复杂.
- 英国现有的关于ICU研究招聘利益相关者的观点的证据有限,需要更好的指导.
研究的目的:
- 收集有关英国利益相关者在招募重症监护室 (ICU) 患者研究方面的观点的证据.
- 制定基于证据的良好实践指南,用于招募重症患者参加临床研究.
- 为了使法律框架与ICU研究的实际情况保持一致,并确保纳入患者/家庭的观点.
主要方法:
- 展望研究调查了1400多个利益相关者,包括患者,亲属和医疗保健从业人员,他们有ICU经验.
- 采用已建立的社会科学方法和经验伦理学来分析利益相关者的利益,并提出建议.
- 利用研究人员和专家咨询小组的意见来解释证据和制定指导.
主要成果:
- 收集了各种利益相关者关于ICU研究招聘的观点的综合数据.
- 确定了获得同意和参与重症监护研究的参与者的关键挑战和促进者.
- 根据经验证据和伦理考虑制定了实用指导.
结论:
- 开发的指南旨在弥合法律要求和ICU研究的实用性之间的差距.
- 确保研究招聘流程反映患者和家人的观点对于道德实践至关重要.
- 本指南为未来的重症监护病房 (ICU) 研究提供了一个框架,以改善招聘策略.
相关概念视频
Ethics in Research
22.9K
Today, scientists agree that good research is ethical in nature and is guided by a basic respect for human dignity and safety. However, this has not always been the case. Modern researchers must demonstrate that the research they perform is ethically sound.
22.9K
Endoscopic Studies II: Thoracocentesis
220
Thoracentesis(Thoracocentesis), commonly known as pleural tap, is a medical procedure where a 22 gauge needle is inserted into the pleural space, the area between the lung and chest wall. This procedure is commonly performed to diagnose or treat various respiratory disorders.
Description
Excess pleural fluid or air may accumulate in some respiratory disorders in the thoracic cavity. To treat pleural effusion, a physician conducts thoracentesis by carefully piercing the chest wall and entering...
Description
Excess pleural fluid or air may accumulate in some respiratory disorders in the thoracic cavity. To treat pleural effusion, a physician conducts thoracentesis by carefully piercing the chest wall and entering...
220
Blind Procedures
10.6K
Ideally, the people who observe and record the children’s behavior are unaware of who was assigned to the experimental or control group, in order to control for experimenter bias. Experimenter bias refers to the possibility that a researcher’s expectations might skew the results of the study. Remember, conducting an experiment requires a lot of planning, and the people involved in the research project have a vested interest in supporting their hypotheses. If the observers knew which...
10.6K
Radiological Investigation II: MRI and Ventilation Perfusion Scan
105
Description
Magnetic Resonance Imaging (MRI) and Ventilation Perfusion Scans are two radiological investigations that offer detailed diagnostic images of the body, particularly lung structures.
MRI
MRI uses magnetic fields and radiofrequency signals to distinguish between normal and abnormal tissues. This technology provides a more detailed diagnostic image than CT scans, enabling it to characterize pulmonary nodules, stage bronchogenic carcinoma, and evaluate inflammatory activity in...
Magnetic Resonance Imaging (MRI) and Ventilation Perfusion Scans are two radiological investigations that offer detailed diagnostic images of the body, particularly lung structures.
MRI
MRI uses magnetic fields and radiofrequency signals to distinguish between normal and abnormal tissues. This technology provides a more detailed diagnostic image than CT scans, enabling it to characterize pulmonary nodules, stage bronchogenic carcinoma, and evaluate inflammatory activity in...
105
Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches
124
Biopharmaceutical studies constitute a vital field aiming to enhance drug delivery methods and refine therapeutic approaches, drawing upon diverse interdisciplinary knowledge. In research methodologies, the choice between controlled and non-controlled studies significantly influences the study's reliability and accuracy.
Non-controlled studies, commonly employed for initial exploration, lack a control group, rendering them susceptible to biases and external influences. In contrast,...
Non-controlled studies, commonly employed for initial exploration, lack a control group, rendering them susceptible to biases and external influences. In contrast,...
124
Data Collection II
8.1K
The nursing history captures and records the patient's health status, so that a care plan evolves to meet the patient's individual needs. The nursing health history is a part of the initial assessment. A comprehensive history covers all health dimensions and plays a significant role in the assessment process. A comprehensive history includes the patient's biographical information, reasons for seeking health care, expectations, present and past health history, medications, and...
8.1K


